This project is part of the work Sam Finnikin and I are doing as part of our fellowship in Evidence and Values at the RCGP.  Essentially:  General practice has seen so many re-disorganisations, contracts, changes and pressures…as well as added workload, and many of us are struggling to love/ do the job we love well. General […]

lovely combination Blood pressure pills at night reproducibility crisis  review article  and old Cochrane review  new study – Hygia project  and trial registration (spot difference) old study and BP levels with diurnal meds – taking (similar bp results, didn’t address morbidity) MAPEC study HEAD LICE Nice guidance  resistance   wet combing   

a history of antidepressant withdrawal 1950s – class of drug called tricyclics started to be used for depression reports of withdrawal side effects in medical literature in 1960s and 70s suggesting slow withdrawals https://journals.sagepub.com/doi/10.1177/070674376601101S27 another class of drugs called MAOIs – again not commonly used nowadays for depression, available in 1950s onwards, lots of interactions […]

these are just notes, sorry! recall affects brand only, prescription only, zantac preparations (i.e. The four products affected are Zantac 150mg/10ml Syrup, Zantac 50mg/2ml Injection, Zantac 150mg Tablets and Zantac 300mg Tablets)  and not the over the counter version of  zantac or other generics of raniditine.  Issues with this contaminant since summer 2018 – issues with […]

NHSE document on prescription restrictions Headlice http://www.bad.org.uk/for-the-public/patient-information-leaflets/head-lice/?showmore=1&returnlink=http%3A%2F%2Fwww.bad.org.uk%2Ffor-the-public%2Fpatient-information-leaflets#.XZR045NKjfY https://www.bmj.com/content/331/7513/384 verucca /warts https://www.ncbi.nlm.nih.gov/pubmed/11686980 out of the chemicals dimeticone best https://www.ncbi.nlm.nih.gov/pubmed/31510998 NSAID gel https://www.cochrane.org/CD007402/SYMPT_topical-non-steroidal-anti-inflammatory-drugs-acute-musculoskeletal-pain-adults Cold sores A Systematic Review on the Efficacy of Topical Acyclovir, Penciclovir, and Docosanol for the Treatment of Herpes Simplex Labialis https://cks.nice.org.uk/herpes-simplex-oral    

the key trials are these two COMPASS and US retrospective study  pharmaceutical journal report medication safety report  NICE guidance growth in DOAC use  other issues https://www.amjmed.com/article/S0002-9343(15)00926-2/fulltext risk of bleeding scores after blood clots https://www.thrombosisresearch.com/article/S0049-3848(17)30047-6/fulltext https://link.springer.com/article/10.1007/s10840-014-9930-y This systematic review focused the high bleeding-risk category of commonly used risk scores in AF. Our main findings were as follows: (1) Overall […]

the key trials are these two COMPASS and US retrospective study  pharmaceutical journal report medication safety report  NICE guidance growth in DOAC use  other issues https://www.amjmed.com/article/S0002-9343(15)00926-2/fulltext risk of bleeding scores after blood clots https://www.thrombosisresearch.com/article/S0049-3848(17)30047-6/fulltext https://link.springer.com/article/10.1007/s10840-014-9930-y This systematic review focused the high bleeding-risk category of commonly used risk scores in AF. Our main findings were as follows: […]

https://www.longtermplan.nhs.uk/online-version/ https://www.england.nhs.uk/2019/09/nhs-to-review-making-statins-available-direct-from-pharmacists-as-part-of-long-term-plan-to-cut-heart-disease/ https://www.nice.org.uk/guidance/cg181/chapter/1-Recommendations#identifying-and-assessing-cardiovascular-disease-cvd-risk-2

The UK is no longer classed as measles-free : The last few years have seen a decline in children having the MMR vaccination. https://www.bmj.com/content/362/bmj.k3967 In 2018 there were 991 confirmed cases of measles in England and Wales, compared with 284 cases in 2017.  This means that the UK has lost it’s measles free status,  which had […]

This is what I said, sorry if it’s disjointed, no point repeating what anyone else has said. So   Royal Patrons – if RCGP ever asked for, must ensure that process includes a commitment to evidence based healthcare 2) China process: concerns this is being seen as a commercial enterprise ; my belief is that […]