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Inside Health 7/7/19 – suncream

  overall advice updated advice here – http://www.bad.org.uk/for-the-public/skin-cancer/sunscreen-fact-sheet debate about UV light, melanoma, and sunscreen https://www.bmj.com/bmj/section-pdf/186530?path=/bmj/337/7663/Head_to_Head.full.pdf background https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041476/ case control study http://cebp.aacrjournals.org/content/early/2010/05/21/1055-9965.EPI-09-1249.abstract review article https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjd.16111 RCT follow up with subgroup analysis https://www.ncbi.nlm.nih.gov/pubmed/21135266 also some evidence re reducing risk of squamous cell carcinoma https://jamanetwork.com/journals/jamadermatology/fullarticle/479276 https://www.cochrane.org/CD011161/SKIN_sun-protection-including-sunscreens-prevent-basal-cell-carcinoma-and-cutaneous-squamous-cell early studies shown sunscreen increased melanoma use https://jamanetwork.com/journals/jamadermatology/article-abstract/478092 bias – in that […]

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prescription payment certificates Inside Health 30/6/19

https://www.nhs.uk/using-the-nhs/help-with-health-costs/get-help-with-prescription-costs/ https://www.nhs.uk/using-the-nhs/help-with-health-costs/save-money-with-a-prescription-prepayment-certificate-ppc/ https://www.gov.uk/government/speeches/nhs-prescription-charges-from-april-2019

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Ovulation and NSAIDs – Inside Health 23/7/19

NSAIDs in pregnancy significant risk of miscarriage –  https://www.ncbi.nlm.nih.gov/pubmed/29890124 (small numbers but one series raised risk from 15% to 23% )  https://www.bmj.com/content/327/7411/368.long science of ovulation and NSAIDS https://link.springer.com/article/10.2165%2F00002018-200225080-00001 https://www.ncbi.nlm.nih.gov/pubmed/16493584 case series 2006 https://www.ncbi.nlm.nih.gov/pubmed/8646437 https://www.ncbi.nlm.nih.gov/pubmed/8624628 https://academic.oup.com/rheumatology/article/39/8/880/1784112 conference abstract, seems to have remained otherwise unpublished Salman S, Sherif B, Al-Zohyri A. Effects of some non steroidal anti-inflammatory […]

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Sperm counts and studies of risk/association Inside Health 16/7/19

Mobile phones and sperm quality smoking *(where are all the other studies there should be on this?) animal research  Hazardous substances advisory committee and WHO  WHO reference ranges over time and overview  Endocrine Society report  and background http://ijomeh.eu/Environmental-exposure-to-non-persistent-endocrine-disrupting-chemicals-and-semen,76451,0,2.html tiny studies looking at dose related effects of  diethylhexyl phthalate (DEHP) and polychlorinated biphenyl 153 (PCB153) https://www.nature.com/articles/s41598-019-39913-9 -> poorer […]

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Obesity and CRUK misguided campaign

for Inside Health 9/7/19 Previous column about similar CRUK campaign  Genetics and obesity  environment, genetics and obesity  CRUK own webpages on preventable risk factors – note alcohol + low fibre diet is a bigger risk factor than obesity…what about messages which are more realistically achieved? weight stigma and healthcare ironic effects of weight stigma perceived […]

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RCGP Council notes 22/6/19

thank you for re-electing me please bear in mind that there is no point repeating stuff someone else has said (unless you like the sound of your own voice etc etc ) so this is just what I said – rules are you can report what you said, not what someone else said, until the […]

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catch up items

Things over the last few months How doctors are peddling pointless vitamin drips  a few things in the Telegraph but all behind a paywall, here  Tell Me Where It Hurts, a programme for Radio 4 about what does/doesn’t/should happen  in GP consultations, and why it’s so important

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More or Less 17/5/19

    https://qrisk.org/2017/index.php https://qintervention.org/index.php https://qrisk.org/three/index.php http://www.assign-score.com/estimate-the-risk/ https://www.nice.org.uk/guidance/cg181/resources/patient-decision-aid-pdf-243780159

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Outcome switching Inside Health 26/3/19

study 329 https://www.sciencedirect.com/science/article/abs/pii/S0890856709603099   https://content.iospress.com/articles/international-journal-of-risk-and-safety-in-medicine/jrs426   http://www.consort-statement.org https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852589/ COMPARE project http://compare-trials.org/faq

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Cannabis products – Inside Health 12/3/19

https://www.nhs.uk/conditions/medical-cannabis/ Government factsheet  MHRA statements  Review referenced by WHO – preclinical/animal studies file:///Users/user/Downloads/2CannabidiolStateoftheartandnewchallengesfortherapeuticapplications.pdf There is a lack of good evidence that any cannabis-derived product works for any chronic neuropathic pain.https://www.cochrane.org/CD012182/SYMPT_cannabis-products-adults-chronic-neuropathic-pain More people reported sleepiness, dizziness and mental problems (e.g. confusion) with all cannabis-based medicines pooled together than with placebo (low-quality evidence) https://www.cochrane.org/CD012954/IBD_cannabis-and-cannabis-oil-treatment-ulcerative-colitis The effects of […]

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