I usually post up what I’ve said. It was a very long meeting. I try not to repeat things that others have said. I contributed towards one paper written by Victoria Tzortziou Brown. My concern is that honours etc given out by college (eg lecturerships, FRCGPs) should be actively trying to increase diversity, the sex […]
Continue Reading →World Service – ovarian cancer screening
Lancet study for UKCTOCS -2021 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00731-5/fulltext and 2015 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01224-6/fulltext Puerto Rico practice https://www.hindawi.com/journals/bmri/2014/920915/ US Preventive services taskforce https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/ovarian-cancer-screening NHS advice on ovarian cancer symptoms https://www.nhs.uk/conditions/ovarian-cancer/
Continue Reading →Yellow Cards
Yellow Card link https://coronavirus-yellowcard.mhra.gov.uk/about Government website on adverse reactions Click to access COVID-19_AstraZeneca_Vaccine_Analysis_Print.pdf York review – history of patient reporting https://aura.abdn.ac.uk/bitstream/handle/2164/2957/mon1520_YCS.pdf;jsessionid=70780E9E705E664188E0B406FFFD2605?sequence=1 https://www.gov.uk/government/publications/coronavirus-covid-19-vaccine-adverse-reactions/coronavirus-vaccine-summary-of-yellow-card-reporting Denmark pause https://www.theguardian.com/society/2021/mar/11/denmark-pauses-astrazeneca-vaccines-to-investigate-blood-clot-reports
Continue Reading →Covid ‘immunity’ ‘vaccination’ ‘testing’ passports
Quarantine – historical https://journals.sagepub.com/doi/pdf/10.1177/003591574503800701 WHO and international vaccine certification https://link.springer.com/chapter/10.1007/978-3-642-73772-5_120 https://journals.sagepub.com/doi/pdf/10.1177/003591574503800701 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454779/ Click to access Green-Book-Chapter-14v2_0.pdf WHO and current guidance https://www.who.int/news-room/articles-detail/interim-position-paper-considerations-regarding-proof-of-covid-19-vaccination-for-international-travellers UK currently reviewing ‘complex issues’ https://www.bbc.co.uk/news/55970801 previous problems with IHR https://journals.sagepub.com/doi/full/10.1177/0098858816658273 loopholes with yellow fever vaccination https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31670-8/fulltext issues with apps and data security https://www.qmul.ac.uk/media/news/2021/se/new-tool-reveals-security-and-privacy-issues-with-contact-tracing-apps.html fantastic tracker from Ada Lovelace Institute https://www.adalovelaceinstitute.org/project/international-monitor-vaccine-passports-covid-status-apps/ Rabies vaccination and […]
Continue Reading →Human Challenge Trials – Inside Health 2nd March 21
Government press release https://www.gov.uk/government/news/worlds-first-coronavirus-human-challenge-study-receives-ethics-approval-in-the-uk Ethical issues https://www.thelancet.com/journals/laninf/article/PIIS1473-30992030438-2/fulltext Pfizer study – the numbers! https://www.nejm.org/doi/full/10.1056/NEJMoa2034577 Nuremberg trials and code https://www.nejm.org/doi/full/10.1056/nejm199711133372006 ethical frameworks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926904/ https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30518-X/fulltext other types human challenge trials hookworm, – https://academic.oup.com/ofid/article/5/5/ofy083/4976553 malaria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195259/ but also RSV – many trials of deliberately infecting humans https://clinicaltrials.gov/ct2/show/NCT02755948 Click to access 77021661.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904492/ Helicobacter story https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661189/ Click to access en_v31n3a02.pdf […]
Continue Reading →Inside Health 23/2/21
Government consultation on ‘minipill’ – POP https://www.gov.uk/government/news/views-sought-on-making-the-oral-contraceptive-pill-desogestrel-available-from-pharmacies recommendations of extended use of implant and (some!) coils https://www.fsrh.org/documents/fsrh-ceu-recommendation-on-extended-use-of-the-etonogestrel/ service standards for family planning+sexual health during covid-19https://www.fsrh.org/documents/fsrh-guidance-essential-srh-services–third-covid-19-lockdown/ and https://www.fsrh.org/documents/fsrh-update-provision-of-contraception-during-covid19/
Continue Reading →prolonged post covid symptoms – Inside Health 16th Feb
NICE /SIGN/RCGP guideline https://www.nice.org.uk/guidance/ng188/chapter/rationales#follow-up-and-monitoring-2 experience with recovery from other eg pneumonia t 50% of people who had pneumonia assessed as having ‘low severity ‘ of illness still experienced fatigue at 3m (mix of in and outpatients) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1497132/ Canadian study patients with pneumonia not admitted to hospital 2/3 better at day 14, half patients back at […]
Continue Reading →What symptoms to test?-Inside Health 9/2/21
CDC symptom checker : https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html (recommends a test if you have a sniffle) ONS Data – 27th Jan https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19infectionsinthecommunityinengland/characteristicsofpeopletestingpositiveforcovid19inengland27january2021 Biobank https://www.ukbiobank.ac.uk/media/x0nd5sul/ukb_serologystudy_report_revised_6months_jan21.pdf RCGP flu surveillance Covid 19 symptom survey https://b6bdcb03-332c-4ff9-8b9d-28f9c957493a.filesusr.com/ugd/3d9db5_bf013154aed5484b970c0cf84ff109e9.pdf
Continue Reading →Mouth/nasal washes and covid-19
iodine based (povidone-iodine) British Dental Journal december worked quickly https://www.nature.com/articles/s41415-020-2402-0- lab based study JAMA https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2770785 lab based study upcoming 40 volunteers Stanford – iodine based nasal sprays in people with covid – measure amount of virus present in nasopharynx https://clinicaltrials.gov/ct2/show/NCT04347954?term=iodine+covid&draw=2&rank=13 theoretical framework https://journalotohns.biomedcentral.com/articles/10.1186/s40463-020-00474-x Nitric oxide releasing solutions – https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-004994-27/GB https://www.royalholloway.ac.uk/about-us/news/new-nasal-spray-proven-to-kill-999-of-the-coronavirus-that-causes-covid-19-is-being-trialled-in-the-uk/ salt water solution ELVIS covid […]
Continue Reading →Screening for covid-19
conclusion: this needs tested, may do more harm than good, and cannot be assumed to ‘work’ Government announcement https://www.gov.uk/government/news/asymptomatic-testing-to-be-rolled-out-across-the-country-starting-this-week including “With the expansion of asymptomatic testing for those unable to work from home, added to our comprehensive COVID-Secure guidance, we can keep our economy on the move while giving individuals in key sectors complete confidence […]
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