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More or Less 7/9/18 – heart age

  Inside Health is off air…and back in a couple of weeks. In the meantime for tonights’ More or Less, here are the main references used for the badly thought out, publicity friendly, potentially harmful screening test that Public Health England didn’t seek advice from the UK National Screening Committee about. No user testing, not […]

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Adrenaline and cardiac arrest

https://www.nejm.org/doi/full/10.1056/NEJMoa1806842 https://www.nejm.org/doi/suppl/10.1056/NEJMoa1806842/suppl_file/nejmoa1806842_appendix.pdf   stuff I’ve written about this trial before in 2014 Adrenaline and cardiac arrest trial – ethics and evidence and I’d like to know how the ethicists who were so opposed to this trial think now that we have evidence of the harm adrenaline has been doing: would they rather we had kept […]

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Infant feeding 17/7/18 Inside Health

https://jamanetwork.com/journals/jamapediatrics/article-abstract/514762   Click to access Infant-sleep-and-night-feeding-during-infancy-2.pdf   Click to access eat-study-final-report-summary.pdf http://cochranelibrary-wiley.com/doi/10.1002/14651858.CD006462.pub4/abstract   https://www.sciencedirect.com/science/article/pii/S1389945718303204   https://www.ncbi.nlm.nih.gov/pubmed/25973527  https://journals.lww.com/jpnnjournal/Abstract/2007/07000/Breast_feeding_Increases_Sleep_Duration_of_New.8.aspx https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995519/ Click to access Statement-on-starting-solids-and-infant-sleep-study-Unicef-UK-Baby-Friendly-Initiative.pdf   The benefits of breastfeeding

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Tamoxifen to prevent breast cancer – Inside Health 3/7/18

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(02)09962-2/fulltext?code=lancet-site .https://www.nice.org.uk/about/what-we-do/our-programmes/nice-guidance/nice-guidelines/making-decisions-using-nice-guidelines#professional-guidelines https://www.nice.org.uk/guidance/cg164   https://www.nice.org.uk/guidance/cg164/chapter/recommendations#breast-cancer-risk-category

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RCGP council 23/6/18

notes from council please note  – there is no point saying something twice, so if other people make the same comment and it’s accepted, it just wastes time to repeat it . This is what I said today Sponsorship review I want the RCGP to stop all sponsorship of the conference and educational modules – […]

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Inside Health 20/3/18 fish oils/adaptive trials

Fish oils: http://www.bbc.co.uk/science/humanbody/mind/articles/intelligenceandmemory/omega_three.shtml http://news.bbc.co.uk/1/hi/england/6991528.stm Fish oil makes children smarter, study claims https://www.telegraph.co.uk/news/health/3083228/Fish-oil-makes-children-smarter-study-claims.html two studies in UK DOLAB 1 and 2 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0043909 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192909 https://theconversation.com/half-of-biomedical-research-studies-dont-stand-up-to-scrutiny-and-what-we-need-to-do-about-that-45149 Click to access 56314e40aac61.pdf adaptive trials: review https://academic.oup.com/jnci/article-abstract/109/6/djx013/3074379?redirectedFrom=fulltext https://academic.oup.com/jnci/article-abstract/109/6/djx013/3074379?redirectedFrom=fulltext https://clinicaltrials.gov/ct2/show/NCT01042379 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706669/ https://www.ncbi.nlm.nih.gov/pubmed/20595245/ https://www.ncbi.nlm.nih.gov/pubmed/25475878    

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Inside Health 13/3/18 – antidepressants and evidence

This whole area is confusing, understudied, and messy. I attach some of the references I used for this area. Never was the term ‘better research is needed’ more fitting…. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140701/   https://www.karger.com/Article/FullText/370338 http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)72262-5/fulltext https://pdfs.semanticscholar.org/7498/9759b62841d088b4b0afc45564aa48e03af7.pdf?_ga=2.238076672.1267186742.1520784025-1252960857.1520784025 .https://nordic.cochrane.org/sites/nordic.cochrane.org/files/public/uploads/theses/Nielsen%20PhD.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627130/ http://www.psychiatrist.com/jcp/article/Pages/2005/v66n10/v66n1015.aspx https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627130/

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