False positives are one of the many banes of screening programmes. In the US, advertising for people to come to private clinics for expensive CT scans, to screen people for lung cancer is common and, of course, legal. Here in the UK, several private companies advertise their services despite COMARE saying that “we have strongly […]
Continue Reading →Who’d be a guinea pig? : column
To be a “guinea pig” in a clinical trial is not an experience people volunteer for lightly. We need only think of the dramatic side-effects of the so-called Elephant Man drug trial at Northwick Park in 2006 to be reminded that volunteers can end up worse off. In that case, there was financial reward for […]
Continue Reading →Never too late…column
How much does willpower have to do with good health? If, for example, we have pursued a life of booze, fags and indolence, can we reverse the damage if we choose to? Or have our prior actions, and our genes, already determined our fate? Some philosophers, particularly the chain-smoking kind, may accept the idea of […]
Continue Reading →Getting to the point
Unfortunately, last week’s column of acupuncture seems to have upset a few people. On the one hand, those who believe in acupuncture have accused me of being unfair to complementary medicine. At the other end of the scale, alternative medicine sceptics have said I am too interested in what acupuncture has to offer. In order to solve this long-running debate once and for all, I’d like […]
Continue Reading →Protect and perfect and not at all convinced
Boots the chemist are making much of research just published in the British Journal of Dermatology. It involves their Protect and Perfect product, which is on sale in my local store, where there are signs saying that customers are allowed to buy only 6 bottles. Clearly they are anticipating great demand. In 2007, the BBC […]
Continue Reading →Making over the pharmaceutical industry
Or perhaps not so much a makeover, but a radical shift in how drug research is decided upon, performed and reported. The suggestions come from Sir Iain Chalmers, who is editor of the James Lind Library in Oxford, and Silvio Garattini, director of the Mario Negri Institute for Pharmacological Research in Milan. Writing in the […]
Continue Reading →Facts: the facts
I was talking to a composer a few weeks ago. “This stuff doesn’t really exist except when it’s played,” he said, pointing to his score with heavy despair. “Whereas you’ve got a job where you can actually see that you are doing something good.” He couldn’t understand that my protests to the contrary were genuine: […]
Continue Reading →Are medical surveys good for our health?
Invitations have been pouring through letterboxes all over the UK to take part in the Biobank. If you haven’t received one already, let me explain what this particular bank wants from you (thankfully, it doesn’t involve money). The Biobank is a research project, and its aim is no less than to improve the “health of […]
Continue Reading →Sir Richard Branson: curious ‘science’ and unfair analogies
Sir Richard recently gave an interview to the BBC when he said, amongst other things, that the healthcare industry could learn from the airline industry; and that all healthcare workers should be screened for MRSA and treated for it because it “is far better than having people dying from unnecessary diseases, and all the misery […]
Continue Reading →Why randomised trials still work best
The only thing separating reiki and reflexology from rational medicine and progress is evidence. And what evidence-based aficionados like me love best is the randomised controlled trial, the process by which most drugs and treatments aspire to be tested. But are we now hearing its death rattle? In a recent lecture at the Royal College […]
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