Government press release
https://www.gov.uk/government/news/worlds-first-coronavirus-human-challenge-study-receives-ethics-approval-in-the-uk
Ethical issues
https://www.thelancet.com/journals/laninf/article/PIIS1473-30992030438-2/fulltext
Pfizer study – the numbers!
https://www.nejm.org/doi/full/10.1056/NEJMoa2034577
Nuremberg trials and code https://www.nejm.org/doi/full/10.1056/nejm199711133372006
ethical frameworks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926904/
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30518-X/fulltext
other types human challenge trials hookworm, –
https://academic.oup.com/ofid/article/5/5/ofy083/4976553
malaria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195259/
but also
RSV –
many trials of deliberately infecting humans
https://clinicaltrials.gov/ct2/show/NCT02755948
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904492/
Helicobacter story https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661189/
Click to access en_v31n3a02.pdf
Common Cold Unit Salisbury – David Tyrrell
Click to access PIIS0140673605667220.pdf
https://medcraveonline.com/JHVRV/re-inventing-the-common-cold-institute-for-the-21st-century.html
so interesting do readhttps://tinyurl.com/bzpwshub
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