18 – relative risks and sinks

relative risks – ace inhibitors

https://www.bmj.com/content/363/bmj.k4209

https://www.bmj.com/company/newsroom/certain-blood-pressure-drugs-linked-to-increased-risk-of-lung-cancer/

https://www.ajkd.org/article/S0272-6386(10)01387-9/pdf

3,186 events in 335,135 patients using ACEI (0.95%)

266 events in 29,008 patients using ARB (0.91%)

Control event rate= 0.0091 FOR ARB

Experimental event rate= 0.0095 FOR acei

ARR = 0.0004 (0.04% absolute risk difference)

whole cohort 7,952 lung cancer events in 992, 061 patients.

patients in our cohort who did not use ACEI or ARBs events =0.007 (absolute 0.07%)

sinks

https://www.ncbi.nlm.nih.gov/books/NBK144018/

https://aricjournal.biomedcentral.com/articles/10.1186/s13756-017-0213-0

https://www.bbc.co.uk/news/uk-scotland-glasgow-west-45567500

https://www.ncbi.nlm.nih.gov/pubmed/2347381

https://www.ncbi.nlm.nih.gov/pubmed/29104124

Ignaz Phillip Semmelweis’ studies of death in childbirth.

http://www.who.int/gpsc/tools/faqs/system_change/en/

Margaret McCartney's Blog