Loneliness references

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503975/

http://www.clinmed.rcpjournal.org/content/5/3/244.long

http://www.pnas.org/content/110/15/5797

http://www.campaigntoendloneliness.org/about-loneliness/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865701/

http://www.biomedcentral.com/1471-2458/13/984

http://onlinelibrary.wiley.com/doi/10.1002/gps.2054/abstract

http://eprints.soton.ac.uk/334648/

Statin references

The diagrams below, from http://www.bmj.com/content/340/bmj.c2442 is  very important.

A good risk calculator would be invisible – it’s shape would overlie perfectly the yellow rectangle where the people who will develop cardiovascular disease over the next decade are represented.

The risk calculators we use are depicted in other colours; Qrisk2 is the best, in pink.

But it is still not very good, meaning that it misses lots of people, and identifies lots of other people at higher risk when they are not.

http://www.bmj.com/content/340/bmj.c2442http://qintervention.org/index.php
http://www.nice.org.uk/nicemedia/live/13637/66547/66547.pdf
http://heart.bmj.com/content/94/1/34.long
http://www.bmj.com/content/335/7611/136
http://www.bmj.com/content/340/bmj.c2197
http://www.bmj.com/content/340/bmj.c2442
http://www.ncbi.nlm.nih.gov/pubmed/21097820
http://www.bmj.com/content/337/bmj.a2286?ijkey=pZoJcnBxda0Ow&keytype=ref
http://www.bmj.com/content/347/bmj.f6123?hwoasp=authn%3A1392759343%3A4130220%3A1366221385%3A0%3A0%3ArU1AwroyVJZUtOEKWO1YdQ%3D%3D
http://www.ncbi.nlm.nih.gov/pubmed/23546564
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004816.pub5/abstract;jsessionid=E73B0348D40FB029610F92007902A564.f02t04