What symptoms to test?-Inside Health 9/2/21

CDC symptom checker : https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html (recommends a test if you have a sniffle) ONS Data – 27th Jan https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19infectionsinthecommunityinengland/characteristicsofpeopletestingpositiveforcovid19inengland27january2021 Biobank https://www.ukbiobank.ac.uk/media/x0nd5sul/ukb_serologystudy_report_revised_6months_jan21.pdf RCGP flu surveillance Covid 19 symptom survey https://b6bdcb03-332c-4ff9-8b9d-28f9c957493a.filesusr.com/ugd/3d9db5_bf013154aed5484b970c0cf84ff109e9.pdf

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Mouth/nasal washes and covid-19

iodine based (povidone-iodine) British Dental Journal december worked quickly https://www.nature.com/articles/s41415-020-2402-0- lab based study JAMA https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/2770785 lab based study upcoming 40 volunteers Stanford – iodine based nasal sprays in people with covid – measure amount of virus present in nasopharynx https://clinicaltrials.gov/ct2/show/NCT04347954?term=iodine+covid&draw=2&rank=13 theoretical framework https://journalotohns.biomedcentral.com/articles/10.1186/s40463-020-00474-x Nitric oxide releasing solutions – https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-004994-27/GB https://www.royalholloway.ac.uk/about-us/news/new-nasal-spray-proven-to-kill-999-of-the-coronavirus-that-causes-covid-19-is-being-trialled-in-the-uk/ salt water solution ELVIS covid […]

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Screening for covid-19

conclusion: this needs tested, may do more harm than good,  and cannot be assumed to ‘work’ Government announcement https://www.gov.uk/government/news/asymptomatic-testing-to-be-rolled-out-across-the-country-starting-this-week including “With the expansion of asymptomatic testing for those unable to work from home, added to our comprehensive COVID-Secure guidance, we can keep our economy on the move while giving individuals in key sectors complete confidence […]

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Vitamin D and Covid-19

initial publications https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgaa733/5934827 UK biobank Our findings do not support a potential link between vitamin D concentrations and risk of COVID-19 infection, nor that vitamin D concentration may explain ethnic differences in COVID-19 infection. https://pubmed.ncbi.nlm.nih.gov/32413819/ Lancet https://www.thelancet.com/journals/landia/article/PIIS2213-8587(20)30268-0/fulltext systematic review on vitamin D supplementation and preventing acute resp infections BMJ 2017 https://www.bmj.com/content/356/bmj.i6583 Meta-analysis of IPD from […]

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2021 ‘trends’ – which do not equal evidence

https://www.cochrane.org/CD003048/INFECTN_do-probiotics-help-treat-acute-infectious-diarrhoea Gut Microbiome (Poo) Testing https://www.bsg.org.uk/strategic-areas/research/gut-microbiota-for-health-expert-panel/ https://pubmed.ncbi.nlm.nih.gov/23439798/ https://www.nature.com/articles/s41591-020-0934-0 https://clevrblends.com/pages/faq https://academic.oup.com/cdn/article/4/Supplement_2/1547/5844467 https://academic.oup.com/cdn/article/4/Supplement_2/1518/5845874 https://www.cell.com/cell/fulltext/S0092-8674(15)01481-6#fig5 https://www.cell.com/cell/fulltext/S0092-8674(15)01481-6#secsectitle0035 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991026/

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how to vaccinate the world – R4 – refs

re compulsory vaccination -links here http://margaretmccartney.com/2019/09/24/compulsory-mmr-inside-health-24919/ Cochrane https://www.cochranelibrary.com/central/doi/10.1002/central/CN-01400885/full https://www.cochrane.org/CD010038/COMMUN_face-face-interventions-inform-or-educate-parents-about-early-childhood-vaccination Canada https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041657/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515949/ trust https://www.sciencedirect.com/science/article/pii/S0264410X1630977X rational questions https://www.bmj.com/content/371/bmj.m4058?ijkey=0e94d3615b1536944c62ffab1d3aa37b30140849&keytype2=tf_ipsecshan MMR and Wales https://www.bmj.com/content/346/bmj.f2598

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RCGP Council 21/11/20

Another council on zoom. It is bizarrely stressful/tiring. anyway Very very pleased to have presented motion to council on appraisal. This was very kindly seconded by Dr Carter Singh who has also been raising concerns for some time. This motion had been several months in the organising and had originated with Carter and myself. A […]

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Inside Health 20/10/20

self taken covid swabs: Canadian review on methods links Californian study in April small self selected group 45 people Australian study in May  NEJM letter 3/6/20 Jama Open June 12th July 22nd JAMA  unsupervised home kits 185 people  Danish study published early Sept – 109 patients October 14th

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Inside Health 13/10/20 – non drug interventions, Test and trace

BESSI collaboration :https://www.bessi-collab.net/about-us SAGE on non drug interventions https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/925854/S0769_Summary_of_effectiveness_and_harms_of_NPIs.pdf rates of covid-19 testing https://coronavirus.data.gov.uk/?_ga=2.54504936.1326017125.1602531867-289927355.1585336355

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Inside Health 11/8/20

flu vaccinations: Green book: Click to access GreenBook_Chapter_19_Influenza_April_2019.pdf Click to access Letter_annualflu_2020_to_2021_update.pdf evidence on effectiveness https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-017-0420-8#:~:text=The%20results%20of%20three%20studies,failure%20in%20persons%20%E2%89%A5%2065 https://www.cochrane.org/news/featured-review-three-updated-cochrane-reviews-assessing-effectiveness-influenza-vaccines https://www.cochrane.org/CD004876/ARI_vaccines-preventing-seasonal-influenza-and-its-complications-people-aged-65-or-older https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005187.pub5/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006484.pub3/full?highlightAbstract=vaccin%7Cvaccines%7Cflu https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008983.pub3/full?highlightAbstract=vaccin%7Cvaccines%7Cflu https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004876.pub4/full https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2019.24.1900121#html_fulltext https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004879.pub5/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001269.pub6/full uptake data Click to access Surveillance_Influenza_and_other_respiratory_viruses_in_the_UK_2019_to_2020_FINAL.pdf https://www.hps.scot.nhs.uk/a-to-z-of-topics/influenza/#data review of covid-19 in children and transmission patterns https://jamanetwork.com/journals/jamapediatrics/fullarticle/2771181

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