ear wax! higher incidence in people with learning disability https://onlinelibrary.wiley.com/doi/full/10.1111/j.1468-3156.2005.00351.x?saml_referrer#b9%20#b10 ear candling – no evidence it works/ some evidence it makes worse by depositing candle wax inside the ear survey of ENT drs – lots reported seeing injuries from use esp burns https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231549/ self ear irrigation devices – bulb syringes used in other european countries […]

NICE fever guidance Different types of consultation /access – good overview

Current NICE guidance https://www.nice.org.uk/guidance/ng136 Lancet meta analysis paper https://www.sciencedirect.com/science/article/pii/S0140673621005900#bib9 See appendix list of trials included -and how few included people with BP under the current NICE range+have no history of heart attack/stroke etc https://ars.els-cdn.com/content/image/1-s2.0-S0140673621005900-mmc1.pdf Cardiac stats

I usually post up what I’ve said. It was a very long meeting. I try not to repeat things that others have said. I contributed towards one paper written by Victoria Tzortziou Brown. My concern is that honours etc given out by college (eg lecturerships, FRCGPs) should be actively trying to increase diversity, the sex […]

Lancet study for UKCTOCS -2021 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00731-5/fulltext and 2015 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01224-6/fulltext Puerto Rico practice https://www.hindawi.com/journals/bmri/2014/920915/ US Preventive services taskforce https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/ovarian-cancer-screening NHS advice on ovarian cancer symptoms https://www.nhs.uk/conditions/ovarian-cancer/

Yellow Card link https://coronavirus-yellowcard.mhra.gov.uk/about Government website on adverse reactions Click to access COVID-19_AstraZeneca_Vaccine_Analysis_Print.pdf York review – history of patient reporting https://aura.abdn.ac.uk/bitstream/handle/2164/2957/mon1520_YCS.pdf;jsessionid=70780E9E705E664188E0B406FFFD2605?sequence=1 https://www.gov.uk/government/publications/coronavirus-covid-19-vaccine-adverse-reactions/coronavirus-vaccine-summary-of-yellow-card-reporting Denmark pause https://www.theguardian.com/society/2021/mar/11/denmark-pauses-astrazeneca-vaccines-to-investigate-blood-clot-reports

Quarantine – historical https://journals.sagepub.com/doi/pdf/10.1177/003591574503800701 WHO and international vaccine certification https://link.springer.com/chapter/10.1007/978-3-642-73772-5_120 https://journals.sagepub.com/doi/pdf/10.1177/003591574503800701 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454779/ Click to access Green-Book-Chapter-14v2_0.pdf WHO and current guidance https://www.who.int/news-room/articles-detail/interim-position-paper-considerations-regarding-proof-of-covid-19-vaccination-for-international-travellers UK currently reviewing ‘complex issues’ https://www.bbc.co.uk/news/55970801 previous problems with IHR https://journals.sagepub.com/doi/full/10.1177/0098858816658273 loopholes with yellow fever vaccination https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31670-8/fulltext issues with apps and data security https://www.qmul.ac.uk/media/news/2021/se/new-tool-reveals-security-and-privacy-issues-with-contact-tracing-apps.html fantastic tracker from Ada Lovelace Institute https://www.adalovelaceinstitute.org/project/international-monitor-vaccine-passports-covid-status-apps/ Rabies vaccination and […]

Government press release https://www.gov.uk/government/news/worlds-first-coronavirus-human-challenge-study-receives-ethics-approval-in-the-uk Ethical issues https://www.thelancet.com/journals/laninf/article/PIIS1473-30992030438-2/fulltext Pfizer study – the numbers! https://www.nejm.org/doi/full/10.1056/NEJMoa2034577 Nuremberg trials and code https://www.nejm.org/doi/full/10.1056/nejm199711133372006 ethical frameworks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926904/ https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30518-X/fulltext other types human challenge trials hookworm, – https://academic.oup.com/ofid/article/5/5/ofy083/4976553 malaria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195259/ but also RSV – many trials of deliberately infecting humans https://clinicaltrials.gov/ct2/show/NCT02755948 Click to access 77021661.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904492/ Helicobacter story https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661189/ Click to access en_v31n3a02.pdf […]

Government consultation on ‘minipill’ – POP https://www.gov.uk/government/news/views-sought-on-making-the-oral-contraceptive-pill-desogestrel-available-from-pharmacies recommendations of extended use of implant and (some!) coils https://www.fsrh.org/documents/fsrh-ceu-recommendation-on-extended-use-of-the-etonogestrel/ service standards for family planning+sexual health during covid-19https://www.fsrh.org/documents/fsrh-guidance-essential-srh-services–third-covid-19-lockdown/ and https://www.fsrh.org/documents/fsrh-update-provision-of-contraception-during-covid19/

NICE /SIGN/RCGP guideline https://www.nice.org.uk/guidance/ng188/chapter/rationales#follow-up-and-monitoring-2 experience with recovery from other eg pneumonia t 50% of people who had pneumonia assessed as having ‘low severity ‘ of illness still experienced fatigue at 3m (mix of in and outpatients) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1497132/ Canadian study patients with pneumonia not admitted to hospital 2/3 better at day 14, half patients back at […]